Loss-of-Function Mutations in MRAP2 Are Pathogenic in Hyperphagic Obesity with Hyperglycemia and Hypertension


Large-scale sequencing of coding exons of MRAP2 in 9,418 adults and adolescents identifies loss-of-function mutations that are associated with monogenic obesity, hypertension and hyperglycemia.

Nature Medicine
Mickaël Canouil
Mickaël Canouil
Head of Biostatistics

Biostatiscian, cinephile and @rlille_rug organiser.