Publications (7 + 36)

Issued Title Journal First Rank
March,
2023 		Contribution of heterozygous PCSK1 variants to obesity and implications for precision medicine: A case-control study The Lancet Diabetes & Endocrinology 16/19
July,
2022 		Epigenetic changes associated with hyperglycaemia exposure in the longitudinal D.E.S.I.R. cohort Diabetes & Metabolism 5/7
June,
2022 		Epigenetic and Transcriptomic Programming of HSC Quiescence Signaling in Large for Gestational Age Neonates International Journal of Molecular Sciences 4/12
May,
2022 		Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation Nature Genetics 90/347
April,
2022 		Rare Variant Analysis of Obesity-Associated Genes in Young Adults With Severe Obesity From a Consanguineous Population of Pakistan Diabetes 12/16
March,
2022 		Maternal Glycemic Dysregulation During Pregnancy and Neonatal Blood DNA Methylation: Meta-analyses of Epigenome-Wide Association Studies Diabetes Care 6/51
February,
2022 		Multi-ancestry genome-wide association study of gestational diabetes mellitus highlights genetic links with type 2 diabetes Human Molecular Genetics 8/73
January,
2022 		Four groups of type 2 diabetes contribute to the etiological and clinical heterogeneity in newly diagnosed individuals: An IMI DIRECT study Cell Reports Medicine 38/60
November,
2021 		Elevated circulating follistatin associates with an increased risk of type 2 diabetes Nature Communications 17/42
October,
2021 		Identification of Key Regions Mediating Human Melatonin Type 1 Receptor Functional Selectivity Revealed by Natural Variants ACS Pharmacology & Translational Science 7/17
September,
2021 		Epigenome-Wide Association Study Reveals Methylation Loci Associated With Offspring Gestational Diabetes Mellitus Exposure and Maternal Methylome Diabetes Care As first or co-first 1/15
June,
2021 		Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci Molecular Psychiatry 73/215
April,
2021 		SHP2 drives inflammation-triggered insulin resistance by reshaping tissue macrophage populations Science Translational Medicine 17/33
February,
2021 		Chromatin 3D interaction analysis of the STARD10 locus unveils FCHSD2 as a regulator of insulin secretion Cell Reports 7/18
January,
2021 		Monogenic diabetes characteristics in a transnational multicenter study from Mediterranean countries Diabetes Research and Clinical Practice 11/24
December,
2020 		Persistent or Transient Human β Cell Dysfunction Induced by Metabolic Stress: Specific Signatures and Shared Gene Expression with Type 2 Diabetes Cell Reports 32/36
December,
2020 		Histone deacetylase 9 promoter hypomethylation associated with adipocyte dysfunction is a statin-related metabolic effect Clinical Epigenetics 3/10
October,
2020 		Pathogenic variants in actionable MODY genes are associated with type 2 diabetes Nature Metabolism 24/27
May,
2020 		General regression model: A “model‐free” association test for quantitative traits allowing to test for the underlying genetic model Annals of Human Genetics 5/11
February,
2020 		NACHO: An R package for quality control of NanoString nCounter data Bioinformatics As first or co-first 1/6
February,
2020 		The expression of genes in top obesity-associated loci is enriched in insula and substantia nigra brain regions involved in addiction and reward International Journal of Obesity 4/17
November,
2019 		Loss-of-function mutations in MRAP2 are pathogenic in hyperphagic obesity with hyperglycemia and hypertension Nature Medicine 29/31
October,
2019 		A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity Human Molecular Genetics 41/97
August,
2019 		A multi-ancestry genome-wide study incorporating gene–smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure Human Molecular Genetics 92/273
July,
2019 		Genome-wide Association Study of Change in Fasting Glucose over time in 13,807 non-diabetic European Ancestry Individuals Scientific Reports 7/48
June,
2019 		Laser capture microdissection of human pancreatic islets reveals novel eQTLs associated with type 2 diabetes Molecular Metabolism As first or co-first 2/20
June,
2019 		Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions American Journal of Epidemiology 79/256
June,
2019 		A catalog of genetic loci associated with kidney function from analyses of a million individuals Nature Genetics 50/291
April,
2019 		Multi-ancestry genome-wide gene–smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids Nature Genetics 96/292
January,
2019 		Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity Nature Communications 72/226
November,
2018 		Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps Nature Genetics 35/114
August,
2018 		Type 2 diabetes–associated variants of the MT \(_{\textrm{2}}\) melatonin receptor affect distinct modes of signaling Science Signaling 9/17
July,
2018 		Increased Hepatic PDGF-AA Signaling Mediates Liver Insulin Resistance in Obesity-Associated Type 2 Diabetes Diabetes As first or co-first 4/38
June,
2018 		Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries PLOS ONE 86/267
June,
2018 		Jointly Modelling Single Nucleotide Polymorphisms With Longitudinal and Time-to-Event Trait: An Application to Type 2 Diabetes and Fasting Plasma Glucose Frontiers in Genetics As first or co-first 1/5
April,
2018 		Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes Nature Genetics 65/237
March,
2018 		A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure The American Journal of Human Genetics 91/288
December,
2017 		Relationship between salivary/pancreatic amylase and body mass index: A systems biology approach BMC Medicine 4/20
June,
2017 		Low-dose exposure to bisphenols A, F and S of human primary adipocyte impacts coding and non-coding RNA profiles PLOS ONE As first or co-first 2/9
June,
2017 		Expression and functional assessment of candidate type 2 diabetes susceptibility genes identify four new genes contributing to human insulin secretion Molecular Metabolism As first or co-first 3/22
February,
2017 		Decreased STARD10 Expression Is Associated with Defective Insulin Secretion in Humans and Mice The American Journal of Human Genetics 9/25
January,
2017 		Hepatic DPP4 DNA Methylation Associates With Fatty Liver Diabetes 7/17
April,
2016 		Variable Clustering in High-Dimensional Linear Regression: The R Package clere The R Journal 4/4
No matching items